Article
Human leukocyte antigen (HLA) pharmacogenomic tests: potential and pitfalls.
Current drug metabolism - 1 Feb 2014
Daly Ann K
Abstract excerpt
Adverse drug reactions involving a range of prescribed drugs and affecting the skin, liver and other organs show strong associations with particular HLA alleles. For some reactions, HLA typing prior to prescription, so that those positive for the risk allele are not given the drug associated with the reaction, shows high positive and negative predictive values. The best example of clinical implementation relates...
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