Article
Tag SNPs for HLA-B alleles that are associated with drug response and disease risk in the Chinese Han population.
The pharmacogenomics journal - 1 Oct 2015
Liu X, Sun J, Yu H, Chen H, Wang J, Zou H, Lu D, Xu J, Zheng S L
Abstract excerpt
Multiple HLA-B alleles (haplotypes) are associated with drug-induced adverse responses and disease risks but are difficult to be directly genotyped. The goal of this study is to identify single nucleotide polymorphisms (SNPs) that are able to tag HLA-B alleles in the Chinese Han population. Twelve HLA-B alleles that are associated with drug adverse responses and disease risks were identified. They were sequenced...
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