Article
Genetic association between adiposity and gout: a Mendelian randomization study.
Rheumatology (Oxford, England) - 1 Dec 2018
Larsson Susanna C, Burgess Stephen, Michaëlsson Karl
Abstract excerpt
Objective: To investigate whether overall obesity (as measured by BMI) and abdominal obesity (as measured by waist-to-hip ratio adjusted for BMI) are associated with gout risk and serum urate concentrations using Mendelian randomization. Methods: Single nucleotide polymorphisms associated with BMI (n = 97) and waist-to-hip ratio adjusted for BMI (n = 49) were analysed for association with gout risk in 2115 gout...
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