Article
Genetic evidence that higher central adiposity causes gastro-oesophageal reflux disease: a Mendelian randomization study
26 May 2020
Abstract excerpt
BACKGROUND: Gastro-oesophageal reflux disease (GORD) is associated with multiple risk factors but determining causality is difficult. We used a genetic approach [Mendelian randomization (MR)] to identify potential causal modifiable risk factors for GORD. METHODS: We used data from 451 097 European participants in the UK Biobank and defined GORD using hospital-defined ICD10 and OPCS4 codes and self-report data (N...
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