Article
Impact of adiposity on risk of female gout among those genetically predisposed: sex-specific prospective cohort study findings over >32 years.
Annals of the rheumatic diseases - 1 Apr 2022
McCormick Natalie, Yokose Chio, Lu Na, Joshi Amit D, Curhan Gary C, Choi Hyon K
Abstract excerpt
OBJECTIVES: To evaluate the joint (combined) association of excess adiposity and genetic predisposition with the risk of incident female gout, and compare to their male counterparts; and determine the proportion attributable to body mass index (BMI) only, genetic risk score (GRS) only, and to their interaction. METHODS: We prospectively investigated potential gene-BMI interactions in 18 244 women from the Nurses'...
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