Article
Identification of Functional Variants in the FAM13A Chronic Obstructive Pulmonary Disease Genome-Wide Association Study Locus by Massively Parallel Reporter Assays.
American journal of respiratory and critical care medicine - 1 Jan 2019
Castaldi Peter J, Guo Feng, Qiao Dandi, Du Fei, Naing Zun Zar Chi, Li Yan, Pham Betty, Mikkelsen Tarjei S, Cho Michael H, Silverman Edwin K, Zhou Xiaobo
Abstract excerpt
RATIONALE: The identification of causal variants responsible for disease associations from genome-wide association studies (GWASs) facilitates functional understanding of the biological mechanisms by which those genetic variants influence disease susceptibility. OBJECTIVE: We aim to identify causal variants in or near the FAM13A (family with sequence similarity member 13A) GWAS locus associated with chronic...
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