Article
Expression and localization of the polarity protein CRB2 in adult mouse brain: a comparison with the CRB1rd8 mutant mouse model.
Scientific reports - 3 Aug 2018
Dolón Jorge F, Paniagua Antonio E, Valle Vicente, Segurado Alicia, Arévalo Rosario, Velasco Almudena, Lillo Concepción
Abstract excerpt
Acquisition of cell polarization is essential for the performance of crucial functions, like a successful secretion and appropriate cell signaling in many tissues, and it depends on the correct functioning of polarity proteins, including the Crumbs complex. The CRB proteins, CRB1, CRB2 and CRB3, identified in mammals, are expressed in epithelial-derived tissues like brain, kidney and retina. CRB2 has a ubiquitous...
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