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Article

Hierarchical control of interleukin 13 (IL-13) signals in lung fibroblasts by STAT6 and SOX11

3 Aug 2018

Abstract excerpt

Interleukin (IL)-13 is a signature cytokine of type 2 inflammation important for the pathogenesis of various diseases, including allergic diseases. Signal transducer and activator of transcription (STAT) 6 is a critical transcriptional factor for the IL-13 signals; however, it remains unknown how expression of the IL-13–induced genes is differentiated by the transcriptional machineries. In this study, we...

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PMID: 30076218
DOI: 10.1074/jbc.ra117.001364

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