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Article

IL-13 deficiency exacerbates lung damage and impairs epithelial-derived type 2 molecules during nematode infection

2020-10-14

Abstract excerpt

IL-13 plays a key role during protective type 2 immune responses at mucosal sites, such as during infection with nematodes. However, dysregulation of IL-13 can also contribute to the pathogenesis of atopic and fibrotic diseases such as allergic asthma. Matrix remodelling is an important component of repair processes in the lung but also a hallmark of chronic conditions involving fibrosis. Hence, understanding the...

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Literature Corpus work
02d33ebf-e12a-575b-a98b-2a2cc7ed615e
DOI
10.1101/2020.10.14.337949
Open publication

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IL-13 deficiency exacerbates lung damage and impairs epithelial-derived type 2 molecules during nematode infectionDOI 10.1101/2020.10.14.337949
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