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Article

Osteoblast AMP-activated protein kinase regulates glucose metabolism and bone mass in adult mice.

Biochemical and biophysical research communications - 10 Sept 2018

Kanazawa Ippei, Takeno Ayumu, Tanaka Ken-Ichiro, Notsu Masakazu, Sugimoto Toshitsugu

Abstract excerpt

Previous studies have shown that AMP-activated protein kinase (AMPK), a crucial regulator of energy homeostasis, plays important roles in osteoblast differentiation and mineralization. However, little is known about in vivo roles of osteoblastic AMPK in glucose metabolism and bone mass regulation in adult mice. Here, we used the inducible Cre system to control the onset of Ampk disruption after birth by removing...

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Identifiers

PMID: 30072101
DOI: 10.1016/j.bbrc.2018.07.141

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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