Article
Mst1/2 Kinases Modulate Glucose Uptake for Osteoblast Differentiation and Bone Formation.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Jun 2018
Li Wenling, Deng Yujie, Feng Bo, Mak Kingston King-Lun
Abstract excerpt
Bone formation and bone homeostasis are energy-expensive processes. How they are being regulated by energy needs is not completely understood. This is of high clinical importance because diabetic-induced bone loss is common whereas the underlying mechanisms are unclear. Here, we show that Mst1/2 are important regulators for glucose uptake during osteoblast differentiation. Genetically removal of both Mst1/2...
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