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Article

AMP-activated protein kinase (AMPK) activation regulates in vitro bone formation and bone mass.

Bone - 1 Aug 2010

Shah M, Kola B, Bataveljic A, Arnett T R, Viollet B, Saxon L, Korbonits M, Chenu C

Abstract excerpt

Adenosine 5'-monophosphate-activated protein kinase (AMPK), a regulator of energy homeostasis, has a central role in mediating the appetite-modulating and metabolic effects of many hormones and antidiabetic drugs metformin and glitazones. The objective of this study was to determine if AMPK can be activated in osteoblasts by known AMPK modulators and if AMPK activity is involved in osteoblast function in vitro...

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Identifiers

PMID: 20399918
DOI: 10.1016/j.bone.2010.04.596
PMCID: PMC3629687

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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