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Regional Diversity in the Postsynaptic Proteome of the Mouse Brain

1 Aug 2018

Abstract excerpt

The proteome of the postsynaptic terminal of excitatory synapses comprises over one thousand proteins in vertebrate species and plays a central role in behavior and brain disease. The brain is organized into anatomically distinct regions and whether the synapse proteome differs across these regions is poorly understood. Postsynaptic proteomes were isolated from seven forebrain and hindbrain regions in mice and...

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PMID: 30071621
DOI: 10.3390/proteomes6030031

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