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An Anatomically Resolved Mouse Brain Proteome Reveals Parkinson Disease-relevant Pathways

2 Feb 2017

Abstract excerpt

in size. The protein expression levels are determined for 6,500 to 7,500 gene protein products from each region and over 12,000 gene protein products for the entire brain, documenting the physiological repertoire of mouse brain proteins in an anatomically resolved and comprehensive manner. We explored the utility of our spatially defined protein profiling methods in a mouse model of Parkinson's disease. We...

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PMID: 28153913
DOI: 10.1074/mcp.m116.061440

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