Article

Developmental dynamics of the postsynaptic proteome to understand synaptic maturation and dysmaturation

2022-05-05

Abstract excerpt

The postsynaptic density (PSD) is a protein condensate composed of ∼1,000 proteins beneath the postsynaptic membrane of excitatory synapses. The number, shape, and plasticity of synapses are altered during development. However, the dynamics of synaptic protein composition across development have not been fully understood. Here we show alterations of PSD protein composition in mouse and primate brains during develo...

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Identifiers and source

Literature Corpus work: 9d654e48-0944-5953-b234-89dc554486c3
DOI: 10.1101/2022.05.05.490828

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