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Article

Impact of genetic variation on synaptic protein levels in genetically diverse mice.

Proteomics - 1 Apr 2016

Loos Maarten, Li Ka Wan, van der Schors Roel, Gouwenberg Yvonne, van der Loo Rolinka, Williams Robert W, Smit August B, Spijker Sabine

Abstract excerpt

The relative abundance of synaptic proteins shapes protein complex formation and is essential for synapse function and behavioral fitness. Here, we have used a panel of highly diverse inbred strains of mice-NOD/LtJ, A/J, 129S1/SvImJ, FVB/NJ, C57BL/6J, WSB/EiJ, PWK/PhJ, and CAST/EiJ-to quantify the effects of genetic variation on the synaptic proteome between strains. Using iTRAQ-based quantitative proteome...

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Source

Identifiers

PMID: 26786964
DOI: 10.1002/pmic.201500154

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CAST

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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