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Article

Synapse proteomics of multiprotein complexes: en route from genes to nervous system diseases.

Human molecular genetics - 15 Oct 2005

Grant Seth G N, Marshall Michael C, Page Keri-Lee, Cumiskey Mark A, Armstrong J Douglas

Abstract excerpt

Proteomic experiments have produced a draft profile of the overall molecular composition of the mammalian neuronal synapse. It appears that synapses have over 1000 protein components and the mapping of their interactions, organization and functions will lead to a global view of the role of synapses in physiology and disease. A major functional subcomponent of the synaptic machinery is a multiprotein complex of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16150739
DOI: 10.1093/hmg/ddi330

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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