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Article

Genetic analysis of the mouse brain proteome.

Nature genetics - 1 Apr 2002

Klose Joachim, Nock Christina, Herrmann Marion, Stühler Kai, Marcus Katrin, Blüggel Martin, Krause Eberhard, Schalkwyk Leonard C, Rastan Sohaila, Brown Steve D M, Büssow Konrad, Himmelbauer Heinz, Lehrach Hans

Abstract excerpt

Proteome analysis is a fundamental step in systematic functional genomics. Here we have resolved 8,767 proteins from the mouse brain proteome by large-gel two-dimensional electrophoresis. We detected 1,324 polymorphic proteins from the European collaborative interspecific backcross. Of these, we mapped 665 proteins genetically and identified 466 proteins by mass spectrometry. Qualitatively polymorphic proteins,...

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Share to Nucleic Acid Hybridization
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Electrophoresis, Gel, Two-Dimensional

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Source

Identifiers

PMID: 11912495
DOI: 10.1038/ng861

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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