SynaptopathyDB integrates synaptic proteomes, genetic and phenotypic data to advance research on nervous system disorders.

Abstract excerpt

Synaptic dysfunction resulting from pathogenic variants in genes encoding synaptic proteins is a major contributor to brain and behavioural disorders, collectively termed synaptopathies. To facilitate research into the genetic basis and clinical manifestations of synaptopathy we have created SynaptopathyDB, an online resource that integrates data from 64 mammalian synapse proteomic studies and multiple genetic...

Topics

• Humans
• Synapses
• Proteome
• Phenotype
• Nervous System Diseases
• Animals
• Proteomics