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Article

Factor VII activating protease. Single nucleotide polymorphisms light the way.

Hamostaseologie - 1 Aug 2011

Kanse S M, Etscheid M

Abstract excerpt

Factor VII activating protease (FSAP) is a circulating serine protease with high homology to fibrinolytic enzymes. A role in the regulation of coagulation and fibrinolysis is suspected based on in vitro studies demonstrating activation of FVII or pro-urokinase plasminogen activator (uPA). However...

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Topics

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Share to Blood Coagulation
Share to Fibrinolysis
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

Share to Serine Endopeptidases

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Source

Identifiers

PMID: 21655671
DOI: 10.5482/ha-1159

Genes

HABP2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21655671-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Factor VII activating protease. Single nucleotide polymorphisms light the way.PMID 21655671Read ↗

Factor VII Activating Protease (FSAP): A Novel Protease in HemostasisSemantic proximity Read ↗

Factor VII-activating protease (FSAP): vascular functions and role in atherosclerosis.Semantic proximity Read ↗

The Marburg I polymorphism of factor VII activating protease is associated with low proteolytic and low pro-coagulant activity.Semantic proximity Read ↗

Factor VII Activating Protease Polymorphism (G534E) Is Associated with Increased Risk for Stroke and MortalitySemantic proximity Read ↗

Genome-wide analysis of genetic determinants of circulating factor VII-activating protease (FSAP) activity.Semantic proximity Read ↗

Plasma factor VII-activating protease antigen levels and activity are increased in ischemic stroke.Semantic proximity Read ↗

Structure-function analysis of factor VII activating protease (FSAP): sequence determinants for heparin binding and cellular functions.Semantic proximity Read ↗

The frequent Marburg I polymorphism impairs the pro-urokinase activating potency of the factor VII activating protease (FSAP).Semantic proximity Read ↗

SNPs in ADAMTS13.Semantic proximity Read ↗

Factor VII activating protease (FSAP) exerts anti-inflammatory and anti-fibrotic effects in liver fibrosis in mice and men.Semantic proximity Read ↗

Genome-Wide Association Analysis of Young-Onset Stroke Identifies a Locus on Chromosome 10q25 Near HABP2.Semantic proximity Read ↗

The factor VII-activating protease (FSAP) enhances the activity of bone morphogenetic protein-2 (BMP-2).Semantic proximity Read ↗

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