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Article

Characterization of the breast cancer resistance protein (BCRP/ABCG2) in clear cell renal cell carcinoma.

International journal of cancer - 15 Dec 2018

Reustle Anna, Fisel Pascale, Renner Olga, Büttner Florian, Winter Stefan, Rausch Steffen, Kruck Stephan, Nies Anne T, Hennenlotter Jörg, Scharpf Marcus, Fend Falko, Stenzl Arnulf, Bedke Jens, Schwab Matthias, Schaeffeler Elke

Abstract excerpt

The efflux transporter breast cancer resistance protein BCRP/ABCG2 is well-known for its contribution to multi-drug resistance in cancer. Its relevance in cancer biology independent from drug efflux remains largely elusive. Our study aimed at elucidating the biological relevance and regulatory mechanisms of BCRP/ABCG2 in clear cell renal cell carcinoma (ccRCC) and disease progression. Two independent...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 30070687
DOI: 10.1002/ijc.31741

Genes

ABCG2
ABCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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