Article
Association of the BCRP C421A polymorphism with nonpapillary renal cell carcinoma.
International journal of cancer - 10 Nov 2005
Korenaga Yoshihito, Naito Katsusuke, Okayama Naoko, Hirata Hiroshi, Suehiro Yutaka, Hamanaka Yuichiro, Matsuyama Hideyasu, Hinoda Yuji
Abstract excerpt
Breast cancer resistance protein (BCRP), the second member of the ATP-binding cassette membrane transporter family, has a single nucleotide polymorphism, C421A (resulting in Q141K), that is of functional importance. Our aim was to explore the relationship between this polymorphism of the BCRP gene and the risk of renal cell carcinoma (RCC) development. For a case-control study, DNA samples from 200 nonpapillary...
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