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Species comparison of liver proteomes reveals links to naked mole-rat longevity and human aging

27 Jul 2018

Abstract excerpt

BACKGROUND: Mammals display a wide range of variation in their lifespan. Investigating the molecular networks that distinguish long- from short-lived species has proven useful to identify determinants of longevity. Here, we compared the livers of young and old long-lived naked mole-rats (NMRs) and the phylogenetically closely related, shorter-lived, guinea pigs using an integrated omics approach. RESULTS: We...

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PMID: 30068331
DOI: 10.1186/s12915-018-0547-y

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