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Long-lived rodents reveal signatures of positive selection in genes associated with lifespan

23 Mar 2018

Abstract excerpt

The genetics of lifespan determination is poorly understood. Most research has been done on short-lived animals and it is unclear if these insights can be transferred to long-lived mammals like humans. Some African mole-rats (Bathyergidae) have life expectancies that are multiple times higher than similar sized and phylogenetically closely related rodents. To gain new insights into genetic mechanisms determining...

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PMID: 29570707
DOI: 10.1371/journal.pgen.1007272

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