Article
Positive selection and climatic effects on MHC class II gene diversity in hares (Lepus capensis) from a steep ecological gradient.
Scientific reports - 31 Jul 2018
Awadi Asma, Ben Slimen Hichem, Smith Steve, Knauer Felix, Makni Mohamed, Suchentrunk Franz
Abstract excerpt
In natural populations, allelic diversity of the major histocompatibility complex (MHC) is commonly interpreted as resulting from positive selection in varying spatiotemporal pathogenic landscapes. Composite pathogenic landscape data are, however, rarely available. We studied the spatial distribution of allelic diversity at two MHC class II loci (DQA, DQB) in hares, Lepus capensis, along a steep ecological...
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