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Article

Both selection and drift drive the spatial pattern of adaptive genetic variation in a wild mammal.

Evolution; international journal of organic evolution - 23 Jan 2023

Lam Derek Kong, Frantz Alain C, Burke Terry, Geffen Eli, Sin Simon Yung Wa

Abstract excerpt

The major histocompatibility complex (MHC) has been intensively studied for the relative effects of different evolutionary forces in recent decades. Pathogen-mediated balancing selection is generally thought to explain the high polymorphism observed in MHC genes, but it is still unclear to what extent MHC diversity is shaped by selection relative to neutral drift. In this study, we genotyped MHC class II DRB...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36626810
DOI: 10.1093/evolut/qpac014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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