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Climate factors and selection shape MHC class II diversity in a montane wild sheep (Ovis ammon).

Immunogenetics - 18 Jun 2026

Tian Zi-Yue, Li Jin-Yi, Cai Zhen-Yuan, Abduriyim Shamshidin

Abstract excerpt

Understanding how environmental heterogeneity drives spatially varying selection is key to deciphering adaptive evolution. The Major Histocompatibility Complex (MHC) provides an ideal model to study this process. We investigated the MHC class II DQA gene across seven subspecies of wild argali sheep (Ovis ammon) in China. High-throughput sequencing of 98 individuals revealed high diversity (25 alleles), with...

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PMID: 42310224
DOI: 10.1007/s00251-026-01405-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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