Article
Selection and demography drive range-wide patterns of MHC-DRB variation in mule deer.
BMC ecology and evolution - 6 Apr 2022
Cook Rachel M, Suttner Brittany, Giglio Rachael M, Haines Margaret L, Latch Emily K
Abstract excerpt
BACKGROUND: Standing genetic variation is important especially in immune response-related genes because of threats to wild populations like the emergence of novel pathogens. Genetic variation at the major histocompatibility complex (MHC), which is crucial in activating the adaptive immune response, is influenced by both natural selection and historical population demography, and their relative roles can be...
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