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Article

Head and neck squamous cell carcinoma drives long interspersed element-1 hypomethylation in the peripheral blood mononuclear cells.

Oral diseases - 1 Jan 2019

Arayataweegool Areeya, Srisuttee Ratakorn, Mahattanasakul Patnarin, Tangjaturonsasme Napadon, Kerekhanjanarong Virachai, Kitkumthorn Nakarin, Mutirangura Apiwat

Abstract excerpt

OBJECTIVE: Alteration of long interspersed element-1 (LINE-1) methylation in peripheral blood mononuclear cells (PBMCs) has been simultaneously activated to breast carcinogenesis due to its secretion. To evaluate the effect in head and neck squamous cell carcinoma (HNSCC), LINE-1 methylation levels and patterns have been measured both in vitro and in vivo. METHODS: Analysis of LINE-1 methylation in cocultured...

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Identifiers

PMID: 30047194
DOI: 10.1111/odi.12944

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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