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LINE-1 hypermethylation in white blood cell DNA is associated with high-grade cervical intraepithelial neoplasia

30 Aug 2017

Abstract excerpt

BACKGROUND: Long Interspersed Nuclear Elements-1 (LINEs-1) methylation from white blood cells (WBCs) DNA has been proposed as biomarker associated with different types of cancer. The aim of the present study was to investigate the degree of WBCs LINE-1 methylation, according to high-risk Human Papilloma Virus (hrHPV) status in a healthy population, and the association with high-grade Cervical Intraepithelial...

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PMID: 28854904
DOI: 10.1186/s12885-017-3582-0

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