Article
LINE-1 and Alu methylation patterns in lymph node metastases of head and neck cancers.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2012
Kitkumthorn Nakarin, Keelawat Somboon, Rattanatanyong Prakasit, Mutirangura Apiwat
Abstract excerpt
BACKGROUND: The potential use of hypomethylation of Long INterspersed Element 1 (LINE-1) and Alu elements (Alu) as a biomarker has been comprehensively assessed in several cancers, including head and neck squamous cell carcinoma (HNSCC). Failure to detect occult metastatic head and neck tumors on radical neck lymph node dissection can affect the therapeutic measures taken. OBJECTIVE: The aim of this study was to...
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