Article
LINE-1 hypermethylation in peripheral blood of cutaneous melanoma patients is associated with metastasis.
Melanoma research - 1 Apr 2015
De Araújo Érica S S, Kashiwabara André Y, Achatz Maria I W, Moredo Luciana F, De Sá Bianca C S, Duprat João P, Rosenberg Carla, Carraro Dirce M, Krepischi Ana C V
Abstract excerpt
Aberrant DNA methylation pattern is a well-known epigenetic marker of cancer cells. Recently, aberrant methylation was also reported in the peripheral blood of cancer patients and it could potentially serve as a biomarker for cancer risk. We investigated the methylation pattern of LINE-1 and other repetitive DNA elements in peripheral blood of cutaneous melanoma patients in order to search for an association with...
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