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Article

Functional characterization of enhancer evolution in the primate lineage.

Genome biology - 25 Jul 2018

Klein Jason C, Keith Aidan, Agarwal Vikram, Durham Timothy, Shendure Jay

Abstract excerpt

BACKGROUND: Enhancers play an important role in morphological evolution and speciation by controlling the spatiotemporal expression of genes. Previous efforts to understand the evolution of enhancers in primates have typically studied many enhancers at low resolution, or single enhancers at high resolution. Although comparative genomic studies reveal large-scale turnover of enhancers, a specific understanding of...

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Identifiers

PMID: 30045748
DOI: 10.1186/s13059-018-1473-6
PMCID: PMC6060477

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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