Article
SEA version 3.0: a comprehensive extension and update of the Super-Enhancer archive.
Nucleic acids research - 8 Jan 2020
Chen Chuangeng, Zhou Dianshuang, Gu Yue, Wang Cong, Zhang Mengyan, Lin Xiangyu, Xing Jie, Wang Hongli, Zhang Yan
Abstract excerpt
Super-enhancers (SEs) are critical for the transcriptional regulation of gene expression. We developed the super-enhancer archive version 3.0 (SEA v. 3.0, http://sea.edbc.org) to extend SE research. SEA v. 3.0 provides the most comprehensive archive to date, consisting of 164 545 super-enhancers. Of these, 80 549 are newly identified from 266 cell types/tissues/diseases using an optimized computational strategy,...
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