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Genes influenced by MEF2C contribute to neurodevelopmental disease via gene expression changes that affect multiple types of cortical excitatory neurons

2019-12-16

Abstract excerpt

Myocyte enhancer factor 2 C (MEF2C) is an important transcription factor during neurodevelopment. Mutation or deletion of MEF2C causes intellectual disability (ID) and common variants within MEF2C are associated with cognitive function and schizophrenia risk. We investigated if genes influenced by MEF2C during neurodevelopment are enriched for genes associated with neurodevelopmental phenotypes, and if this can...

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Identifiers and source

Literature Corpus work
8abb478a-0a40-5b78-9f54-49965471ec98
DOI
10.1101/2019.12.16.877837
Open publication

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Genes influenced by MEF2C contribute to neurodevelopmental disease via gene expression changes that affect multiple types of cortical excitatory neuronsDOI 10.1101/2019.12.16.877837
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