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Article

Marginal screening of 2 × 2 tables in large-scale case-control studies.

Biometrics - 1 Mar 2019

McKeague Ian W, Qian Min

Abstract excerpt

Assessing the statistical significance of risk factors when screening large numbers of 2×2 tables that cross-classify disease status with each type of exposure poses a challenging multiple testing problem. The problem is especially acute in large-scale genomic case-control studies. We develop a potentially more powerful and computationally efficient approach (compared with existing methods, including Bonferroni...

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Identifiers

PMID: 30039847
DOI: 10.1111/biom.12957
PMCID: PMC6666403

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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