Article
Resampling-based multiple hypothesis testing procedures for genetic case-control association studies.
Genetic epidemiology - 1 Sept 2006
Chen Bingshu E, Sakoda Lori C, Hsing Ann W, Rosenberg Philip S
Abstract excerpt
In case-control studies of unrelated subjects, gene-based hypothesis tests consider whether any tested feature in a candidate gene--single nucleotide polymorphisms (SNPs), haplotypes, or both--are associated with disease. Standard statistical tests are available that control the false-positive rate at the nominal level over all polymorphisms considered. However, more powerful tests can be constructed that use...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.