Genome shuffling and high-throughput screening of Brevibacterium flavum MDV1 for enhanced L-valine production.

doi:10.1007/s11274-018-2502-z

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Genome shuffling and high-throughput screening of Brevibacterium flavum MDV1 for enhanced L-valine production.

World journal of microbiology & biotechnology - 23 Jul 2018

Huang Qin-Geng, Zeng Bang-Ding, Liang Ling, Wu Song-Gang, Huang Jian-Zhong

Abstract excerpt

L-valine is an essential branched-amino acid that is widely used in multiple areas such as pharmaceuticals and special dietary products and its use is increasing. As the world market for L-valine grows rapidly, there is an increasing interest to develop an efficient L-valine-producing strain. In this study, a simple, sensitive, efficient, and consistent screening procedure termed 96 well plate-PC-HPLC (96-PH) was...

Topics

Aziridines
Batch Cell Culture Techniques
Biomass
Bioreactors
Brevibacterium flavum
DNA Shuffling
Fermentation
Genome, Bacterial
Genomic Instability
Glucose
High-Throughput Screening Assays

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Industrial Microbiology

Membrane Fusion

Mutagenesis

Mutation

Protoplasts

Time Factors

Ultraviolet Rays

Source

Open in PubMed

Identifiers

PMID: 30039311
DOI: 10.1007/s11274-018-2502-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome shuffling and high-throughput screening of Brevibacterium flavum MDV1 for enhanced L-valine production.PMID 30039311Read ↗

Screening of high glucose tolerant Escherichia coli for L-valine fermentation by autonomous evolutionary mutation.Semantic proximity Read ↗

Fed-batch culture of Escherichia coli for L-valine production based on in silico flux response analysis.Semantic proximity Read ↗

Improvement of industrially important microbial strains by genome shuffling: Current status and future prospects.Semantic proximity Read ↗

[Advances in microbial production of 5-aminolevulinic acid].Semantic proximity Read ↗

Tools for genome-wide strain design and construction.Semantic proximity Read ↗

Genome shuffling for phenotypic improvement of industrial strains through recursive protoplast fusion technology.Semantic proximity Read ↗

A Brief Guide to the High-Throughput Expression of Directed Evolution Libraries.Semantic proximity Read ↗

Developing a Nanopore Sequencing Workflow for Protein Engineering Applications.Semantic proximity Read ↗

Tn5 Transposon-based Mutagenesis for Engineering Phage-resistant Strains of Escherichia coli BL21 (DE3).Semantic proximity Read ↗

Genome shuffling of Streptomyces viridochromogenes for improved production of avilamycin.Semantic proximity Read ↗

Biosensor-driven adaptive laboratory evolution of l-valine production in Corynebacterium glutamicum.Semantic proximity Read ↗

Methods for enzyme library creation: Which one will you choose?: A guide for novices and experts to introduce genetic diversity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.