Article
Genome shuffling and high-throughput screening of Brevibacterium flavum MDV1 for enhanced L-valine production.
World journal of microbiology & biotechnology - 23 Jul 2018
Huang Qin-Geng, Zeng Bang-Ding, Liang Ling, Wu Song-Gang, Huang Jian-Zhong
Abstract excerpt
L-valine is an essential branched-amino acid that is widely used in multiple areas such as pharmaceuticals and special dietary products and its use is increasing. As the world market for L-valine grows rapidly, there is an increasing interest to develop an efficient L-valine-producing strain. In this study, a simple, sensitive, efficient, and consistent screening procedure termed 96 well plate-PC-HPLC (96-PH) was...
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