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Article

PDGFRA gene, maternal binge drinking and obstructive heart defects.

Scientific reports - 23 Jul 2018

Tang Xinyu, Eberhart Johann K, Cleves Mario A, Li Jingyun, Li Ming, MacLeod Stewart, Nembhard Wendy N, Hobbs Charlotte A

Abstract excerpt

Obstructive heart defects (OHDs) are a major health concern worldwide. The platelet-derived growth factor (PDGF) genes are known to have regulatory functions that are essential for proper heart development. In a zebrafish model, Pdgfra was further demonstrated to interact with ethanol during craniofacial development. In this article, we investigated interactions between variants in PDGF genes and periconceptional...

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Share to PDGFRA gene
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Heart Defects, Congenital

Share to Polymorphism, Single Nucleotide

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Share to Prenatal Exposure Delayed Effects

Share to Receptor, Platelet-Derived Growth Factor alpha

Source

Open in PubMed Open full text

Identifiers

PMID: 30038270
DOI: 10.1038/s41598-018-29160-9
PMCID: PMC6056529

Genes

PDGFRA
PDGFA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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