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Article

Associations of genetic variation and mRNA expression of PDGF/PDGFRB pathway genes with coronary artery disease in the Chinese population.

Journal of cellular and molecular medicine - 1 Nov 2024

Wei Pengfei, Xie Hankun, Sun Junxiang, Zhuang Qian, Xie Jichao, Yin Yunjie, Liu Fangyuan, Li Wen, Chen Changying, Wang Feifan, Han Xu, Xu Liang, Zhao Xianghai, Chen Yanchun, Yang Song, Shen Chong

Abstract excerpt

Platelet-derived growth factors (PDGFs) and receptors (PDGFR) play a key role in the process of coronary atherosclerosis. We aimed to investigate the association of genetic variations and mRNA expressions of PDGF/PDGFRB pathway genes with coronary artery disease (CAD). In this case-control study (3139 CAD vs. 3270 controls), 13 single nucleotide polymorphisms (SNPs) at five pathway genes were genotyped and...

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Identifiers

PMID: 39569832
DOI: 10.1111/jcmm.70193
PMCID: PMC11579943

Genes

CAD
PDGFRB
PDGFA
PDGFB
PDGFC
PDGFD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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