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Article

Genetic vulnerabilities to prenatal alcohol exposure: Limb defects in sonic hedgehog and GLI2 heterozygous mice.

Birth defects research - 3 Jul 2017

Fish Eric W, Murdaugh Laura B, Sulik Kathleen K, Williams Kevin P, Parnell Scott E

Abstract excerpt

BACKGROUND: Genetic factors influence the physical and neurobehavioral manifestations of prenatal alcohol exposure (PAE). Animal models allow the investigation of specific genes that confer vulnerability to, or protection from, birth defects associated with fetal alcohol spectrum disorders (FASDs). The objective of the present experiments was to determine if genetic alterations in the Sonic Hedgehog (Shh)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Kruppel-Like Transcription Factors

Share to Limb Deformities, Congenital

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Source

Open in PubMed Open full text

Identifiers

PMID: 28504423
DOI: 10.1002/bdr2.1026
PMCID: PMC5495621

Genes

GLI2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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