Article
rs1800796 of the IL6 gene is associated with increased risk for anti-tuberculosis drug-induced hepatotoxicity in Chinese Han children.
Tuberculosis (Edinburgh, Scotland) - 1 Jul 2018
Li Yingjia, Tang Haijing, Qi Hui, Shen Chen, Sun Lin, Li Jieqiong, Xu Fang, Jiao Weiwei, Yang Xu, Shen Adong
Abstract excerpt
Previous studies have revealed the important contribution of the immune response and oxidative stress to the development of anti-tuberculosis drug-induced hepatotoxicity (ATDH). To investigate whether single-nucleotide polymorphisms (SNPs) of the cytokine gene interleukin-6 (IL6) and oxidative stress genes xanthine dehydrogenase/oxidase (XO) and inducible nitric oxide synthase (NOS2) were associated with...
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