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Article

Analysis of IL-6, STAT3 and HSPA1L gene polymorphisms in anti-tuberculosis drug-induced hepatitis in a nested case-control study.

PloS one - 1 Jan 2015

Wang Jing, Chen Ru, Tang Shaowen, Lv Xiaozhen, Wu Shanshan, Zhang Yuan, Xia Yinyin, Gao Pei, Tu Dehua, Chen Dafang, Zhan Siyan

Abstract excerpt

OBJECTIVES: To investigate the association of IL-6, STAT3 and HSPA1L polymorphisms with the risk of anti-tuberculosis drug-induced hepatitis (ATDH) in Chinese Han population. METHODS: The study was designed as a nested case-control study within a prospective cohort. Each case was matched with four controls by sex, age at baseline (±5 years), treatment history, disease severity, drug dosage and place of sample...

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Source

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Identifiers

PMID: 25789467
DOI: 10.1371/journal.pone.0118862
PMCID: PMC4366259

Genes

STAT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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