Article
Association of ABCB6 Polymorphisms and Serum Levels with Susceptibility to Antituberculosis Drug-induced Hepatotoxicity.
Journal of gastrointestinal and liver diseases : JGLD - 27 Mar 2025
Chen Ruina, Cheng Jingru, Pan Hongqiu, Lu Lihuan, He Xiaomin, Zhang Meiling, Yi Honggang, Tang Shaowen
Abstract excerpt
BACKGROUND AND AIMS: The occurrence of anti-tuberculosis drug-induced hepatotoxicity (ATDH) deserves our attention. To explore the role of ATP-binding cassette B6 (ABCB6) polymorphisms and serum levels in the risk of antituberculosis drug-induced hepatotoxicity (ATDH). METHODS: A 1:4 matched case‒control study was conducted. Four single nucleotide polymorphisms (SNPs) and serum ABCB6 levels were analyzed, and...
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