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Genetic variants in antioxidant pathway: risk factors for hepatotoxicity in tuberculosis patients.

Tuberculosis (Edinburgh, Scotland) - 1 May 2012

Nanashima Kazutaka, Mawatari Tsutomu, Tahara Naoko, Higuchi Norihide, Nakaura Ayano, Inamine Tatsuo, Kondo Shinji, Yanagihara Katsunori, Fukushima Kiyoyasu, Suyama Naofumi, Kohno Shigeru, Tsukamoto Kazuhiro

Abstract excerpt

Tuberculosis (TB) treatment can cause serious sequelae including adverse effects such as anti-TB drug-induced hepatotoxicity (ATDH). We performed a candidate gene-based association study between single nucleotide polymorphisms (SNPs) in 10 genes in the antioxidant pathway and ATDH susceptibility....

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Identifiers

PMID: 22341855
DOI: 10.1016/j.tube.2011.12.004

Genes

BACH1
MAFK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22341855-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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