Article
Interleukin-4 and interleukin-10 polymorphisms and antituberculosis drug-induced hepatotoxicity in Chinese population.
Journal of clinical pharmacy and therapeutics - 1 Apr 2015
Wang J, Chen R, Tang S, Lv X, Wu S, Zhang Y, Yang Z, Xia Y, Chen D, Zhan S
Abstract excerpt
WHAT IS KNOWN AND OBJECTIVE: Evidence demonstrates that the delicate balance between pro- and anti-inflammatory cytokines determines the further progress to severe injury or recovery. Therefore, understanding which cytokines are associated with the development of drug-induced hepatotoxicity (DIH) might guide the prevention and therapeutic direction. Some polymorphisms of cytokine genes have been reported to be...
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