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Article

Nuclear-Mitochondrial interactions influence susceptibility to HIV-associated neurocognitive impairment.

Mitochondrion - 1 May 2019

Smieszek S, Jia P, Samuels D C, Zhao Z, Barnholtz-Sloan J, Kaur H, Letendre S, Ellis R, Franklin D R, Hulgan T, Kallianpur A, Bush W S

Abstract excerpt

HIV-associated neurocognitive impairment (NCI) is a term established to capture a wide spectrum of HIV related neurocognitive deficits ranging in severity from asymptomatic to dementia. The genetic underpinnings of this complex phenotype are incompletely understood. Mitochondrial function has long been thought to play a role in neurodegeneration, along with iron metabolism and transport. In this work, we aimed to...

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Source

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Identifiers

PMID: 30026132
DOI: 10.1016/j.mito.2018.07.004
PMCID: PMC6336535

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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