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Mitochondrial DNA Haplogroups and Neurocognitive Impairment During HIV Infection

30 Jun 2015

Abstract excerpt

BACKGROUND: Neurocognitive impairment (NCI) remains an important complication in persons infected with human immunodeficiency virus (HIV). Ancestry-related mitochondrial DNA (mtDNA) haplogroups have been associated with outcomes of HIV infection and combination antiretroviral therapy (CART), and with neurodegenerative diseases. We hypothesize that mtDNA haplogroups are associated with NCI in HIV-infected adults...

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PMID: 26129753
DOI: 10.1093/cid/civ527

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