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Article

PD-1 genotype of the donor is associated with acute graft-versus-host disease after HLA-identical sibling donor stem cell transplantation.

Annals of hematology - 1 Nov 2018

Santos Nazly, Rodríguez-Romanos Rocío, de la Cámara Rafael, Brunet Salut, Nieto Jose B, Buño Ismael, Martínez Carmen, Jiménez-Velasco Antonio, Vallejo Carlos, González Marcos, Solano Carlos, Ferrá Christelle, Sampol Antonia, Pérez-Simón Jose A, López-Jiménez Javier, Díez José L, Gallardo David

Abstract excerpt

Programmed death 1 (PD-1) activation triggers an immune checkpoint resulting in inhibition of T cells that leads to peripheral tolerance. Some PD-1 polymorphisms have been described and associated with the development of autoimmune diseases or cancer predisposition, but there are few data concerning the relevance of such polymorphisms on the clinical outcome after allogeneic hematopoietic stem cell transplant...

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Source

Identifiers

PMID: 30019128
DOI: 10.1007/s00277-018-3438-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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