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Article

Review of Genetic Variation as a Predictive Biomarker for Chronic Graft-Versus-Host-Disease After Allogeneic Stem Cell Transplantation.

Frontiers in immunology - 1 Jan 2020

Partanen Jukka, Hyvärinen Kati, Bickeböller Heike, Bogunia-Kubik Katarzyna, Crossland Rachel E, Ivanova Milena, Perutelli Francesca, Dressel Ralf

Abstract excerpt

Chronic graft-versus-host disease (cGvHD) is one of the major complications of allogeneic stem cell transplantation (HSCT). cGvHD is an autoimmune-like disorder affecting multiple organs and involves a dermatological rash, tissue inflammation and fibrosis. The incidence of cGvHD has been reported to be as high as 30% to 60% and there are currently no reliable tools for predicting the occurrence of cGvHD. There is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33193367
DOI: 10.3389/fimmu.2020.575492
PMCID: PMC7604383

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